Who We Are:

Genesis Genetics Institute is the pioneer of pre-implantation testing of embryos for inherited genetic abnormalities. Founded by world renowned scientist Dr. Mark Hughes MD, PhD., our team of genetic counselors, molecular geneticists, physicians and administrative staff work closely with your reproductive doctors to fulfill our mission: helping couples build healthy families. Throughout our locations in the United States, and globally in Brazil, England, Jordan and Taiwan thousands of families have achieved this dream with our help. Their photographs cover walls and their stories inspire us.

What is “Genesis-24?”

Genesis-24, also known as Pre-Implantation Genetic Screening (PGS), is a procedure designed to examine your embryos for chromosome abnormalities. Genesis-24 examines all 24 chromosomes—the 22 non-sex chromosomes plus the 2 sex chromosomes (X & Y) in time for your embryo transfer. Chromosome abnormalities may result in aneuploidy (wrong number-e.g. Down Syndrome), translocations (incorrect chromosome position), or other structural alterations that may be clinically significant.

Why is this technology important?

Genesis-24 screening is typically prescribed for couples of advanced maternal age, known familial translocations/inversions, gene duplications, and deletions, or families who have had recurrent pregnancy losses both naturally and through IVF.

Genesis-24 aims at improving pregnancy rate by testing your embryos for chromosome abnormalities—an increasing problem for families who choose to have children later in life. Without Genesis-24, embryos are chosen based on their visual quality and morphology alone. In cycles that incorporate Genesis-24, embryos are further assessed based on their chromosome compliment. Embryos with the normal number of chromosomes are more likely to result in pregnancy that is carried to term. Our rapid, accurate and confidential testing allows our patients to have fresh embryo transfers with the peace of mind that their embryos are chromosomally normal on day one of their pregnancy.

How is this technology performed?

Genesis-24 screening utilizes the most sophisticated and scientifically validated technology for determining the chromosome compliment in a cell. Comparative Genomic Hybridization (CGH) is a microarray technology that compares the DNA in the embryo sample to a known normal control using tens of thousands of genetic markers throughout the human genome. Data is obtained which results in a computer-generated chromosome map for each embryo sample. Our trained scientists interpret the data and provide a detailed genetic report to your IVF physicians in time for your embryo transfer.

Genesis-24 technology is so sophisticated that

• Embryos do not needed to be frozen
• Embryo can be transferred in the same IVF cycle
• Support from parental DNA is not required
• No set-up is required—patients can decide after their egg retrieval to proceed with testing
• This technology is the standard around Europe and the U.S.A. and the only technology accepted by the European Society of Human Reproduction and Embryology (ESHRE)

Contact one of our genetic counselors for more information about Genesis-24. Call us at 313-579-9650 or email us at counselor@genesisgenetics.org

 

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